No.
From what I know, if you are taking cannabis orally for medicinal purposes (i.e. dealing with pain etc.), then you don't want to decarb because you will need the maximum active compounds available.
When you decarb you process for example THC to THC-a (or something, sorry going by what I have memorized and that might not be entirely accurate).
The purpose is not to make compounds available but to get that "stone" effect that most people are after.
Again, as I am typing this I am becoming more and more sure I am mixing things up here or making mistakes.
Maybe just look on youtube for cheff butt (yes, that's his name).
Stumbled across him for his cannabutter recipe.
If you look at his "revised" cannabutter recipe, he will explain the whole decarbing or no decarbing thing.
But to summarize:
If you are doing it for medicine, don't decarb. If you are doing it for funsies, decarb.