After the harvest, of course. Today, I am getting ready to fire up some Afgooey. Rumor has it Afgooey was created in the 1980's from Maui Haze and a Afghani landrace. I wasn't there so I can't vouch for that. I can vouch for its potency and earthy pine smell and taste with hints of wood and sweetness. Very potent smell so the smallest bud will stink up your entire house if not put in an airtight container. Putting it in a baggie at the bottom of your underwear drawer won't cut it. Your house will smell of Afgooey! If not careful with it, it's 'lights out' before you know what hit you. This make it a good choice for chronic pain or insomnia. Or both!